DEXERYL Emollient Cream

DEXERYL Emollient Cream

Statistically significant effectiveness proven in clinical studies on over 1000 patients. These studies were done against a placebo or comparator, providing the highest level of scientific evidence.

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DEXERYL: an effective treatment for dry skin in the context of kidney failure

73% of patients significantly improved their dry skin caused by kidney failure

With regular application of Dexeryl Emollient Cream twice a day on the body, 73% of patients saw their xerosis greatly improved or completely cured after 7 days¹.

md_dexeryl_website-uremic-xerosis-results-graph 577x549 v2 Percentage of patients in complete or near-complete remission with placebo or DEXERYL Emollient Cream.

-75%

itching after 2 months of treatment¹

82%

of patients satisfied to very satisfied¹

1- Balaskas et al. Randomized, Double-blind Study with Glycerol and Paraffin in Uremic Xerosis. Clin J Am Soc Nephrol. 2011

METHODOLOGY

Aim

To evaluate the efficacy of glycerin-paraffin cream on uraemic xerosis.  

Study

Randomised, double-blind, intra-individual (left versus right), multi-centre clinical study comparing a glycerin-paraffin cream on uraemic xerosis.

Population

99 randomised patients with moderate to severe uraemic xerosis.

Dosage

2 applications daily.

Duration

8 weeks

Primary evaluation criteria

Treatment response (xerosis score) on each leg, as defined by a reduction of at least two grades in five points from baseline in the clinical score on day 7.

Secondary evaluation criteria

  • Patient self-assessment of overall pruritus (visual analogue scale: VAS) and quality of life (SF-12 and DLQI scales).
  • Local tolerance, cosmetic acceptability assessed by patients.
  • Overall tolerability as assessed by the investigators

Tolerance

DEXERYL is safe and well-accepted.

Uraemic xerosis: causes, symptoms and treatments

Uraemic xerosis: causes, symptoms and treatments

Uraemic xerosis is the scientific term for skin dryness related to dialysis treatment. It is accompanied by severe pruritus.

Find out more about uraemic xerosis

Sources:  

1- Balaskas et al. Randomized, Double-blind Study with Glycerol and Paraffin in Uremic Xerosis. Clin J Am Soc Nephrol. 2011

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