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DEXERYL supports you and take care of your dry skin each day
- CLINICAL RESULTS
- About dexeryl
DEXERYL supports you and take care of your dry skin each day
Statistically significant effectiveness proven in clinical studies on over 1000 patients. These studies were done against a placebo or comparator, providing the highest level of scientific evidence.
Percentage of patients with at least a 50% reduction in SRRC score at D28 (%). SRRC Score = Scaling Roughness Redness Cracks score: reference score for assessing skin dryness and ichthyosis based on these four criteria. Graphic created by Pierre Fabre.
of patients rated hydration as good or very good1,2
of patients consider that sweating has improved slightly or considerably1,2
of physicians in the clinical study found DEXERYL Emollient Cream to be effective in the management of ichthyosis in children1,2
To demonstrate the effectiveness of DEXERYL Emollient Cream in reducing the severity of ichthyosis.
Phase III, international, multicentre, randomised, controlled, double-blind, parallel-group study: Dexeryl versus vehicle (placebo).
231 children included with an average age of 8.3 years, suffering from a non-bullous form of ichthyosis: ichthyosis vulgaris (63.2%), X-linked recessive (14.7%), other (22.1%).
2 applications daily.
12 weeks (4-week double-blind period with Dexeryl Cream or vehicle) followed by an open-label period with all patients treated with Dexeryl Cream (for 8 weeks).
Improvement of ichthyosis by monitoring the evolution of skin xerosis via the SRRC* score : percentage of patients with a 50% reduction in SRRC score at D28.
Pruritus: assessed using a visual analogue scale (VAS). Global assessment (hydration capacity, improvement of perspiration): performed by each investigator and patient.
Twice-daily application of DEXERYL cream to the skin of children for 3 months did not induce any systemic or local adverse effects. DEXERYL cream has, therefore, proven to be safe and has a good tolerance profile.
Ichthyosis? We should talk about ichthyosis because there are several forms of it of varying severity1,2. Ichthyosis is a rare genetic skin disease characterised by very dry skin and a fish-scale appearance. But what is ichthyosis?
Sources:
1 - Blanchet-Bardon C et al. Association of glycerol and paraffin in the treatment of ichthyosis in children: an international, multicentric, randomized, controlled, double-blind study. JEADV 2012